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Tarextumab

(Synonyms: OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody)
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Tarextumab (OMP-59R5) is a cross-reactive, fully human IgG2 antibody that selectively inhibits Notch2 and Notch3 signaling. Tarextumab demonstrates broad-spectrum antitumor efficacy in xenograft models of epithelial tumors. Tarextumab can be used for the study of pancreatic cancer.

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  • Pureté: 99.83%
  • CAS No.: 1359940-55-8
  • Masse moléculaire:142.94 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tarextumab
  • Experimental Validation Results for Tarextumab
  • Experimental Validation Results for Tarextumab
  • Tarextumab Chemical Structure
    Tarextumab Chemical Structure
CAS No.: 1359940-55-8
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Tarextumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized NOTCH2 Protein (His Tag), Human can bind Tarextumab. The EC50 for this effect is 1.22 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 MCF-7 cells with Tarextumab (HY-P99320, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tarextumab Chemical Structure
    1/16
  • Tarextumab
  • Immobilized NOTCH2 Protein (His Tag), Human can bind Tarextumab. The EC50 for this effect is 1.22 ng/mL.
  • Flow cytometric analysis of 1X106 MCF-7 cells with Tarextumab (HY-P99320, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).