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Cat. No.: HY-111281

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UK 39671

UK 39671 is a store-operated calcium permeability inhibitor with an IC₅₀ of 10 μM in thymocytes. UK 39671 prevents the acceleration of Mn²⁺ influx in thymocytes with intracellular calcium store depletion.

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CAS No.: 85473-17-2
Formule: C₁₇H₂₂Cl₂N₂O
Masse moléculaire:341.28

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Please store the product under the recommended conditions in the Certificate of Analysis.

UK 39671 Chemical Structure

CAS No.: 85473-17-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
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Activité biologique

Description

In Vitro

UK 39671 (10 μM) potently inhibits store-regulated plasma membrane Ca²⁺/Mn²⁺ permeability in rat thymocytes with an IC₅₀ of 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

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Chemical Information

CAS No. 85473-17-2
Masse moléculaire 341.28
Formule C₁₇H₂₂Cl₂N₂O
SMILES

ClC1=CC=C(C(Cl)=C1)C(O)(CN2C=NC=C2)CCCCCC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Alvarez J, et al. Cytochrome P450 may regulate plasma membrane Ca2+ permeability according to the filling state of the intracellular Ca2+ stores. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1992 Jan 06;6(2):786-92. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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