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United States

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Cat. No.: HY-157013

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UR-MB-355

UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₅₄H₅₄ClF₃N₈O₈
Masse moléculaire:1035.50

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

UR-MB-355 Chemical Structure

Stock

Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities^[1].

IC₅₀ & Target

pEC50：6.05 (at Nluc-GPR3)^[1].

Chemical Information

Masse moléculaire 1035.50
Formule C₅₄H₅₄ClF₃N₈O₈
SMILES

ClC1=CC(OC(C)C)=C(C=C1)CNC2=CC(C3=CC=CC=C3OCCCCCCNC(C4=CC(C([O-])=O)=C(C=C4)C5=C6C=CC(N(C)C)=CC6=[O+]C7=C5C=CC(N(C)C)=C7)=O)=NC8=NC=NN28.O=C(O)C(F)(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Merlin Bresinsky, et al. Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. J Med Chem. 2023 Nov 9;66(21):15025-15041. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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