Valiolamine
Based on 1 Customer Validation
Valiolamine, an aminocyclitol, is an alpha-glucosidase inhibitor. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase. Valiolamine binds to porcine intestinal maltase and sucrase with Ki values of 350 nM and 30 nM, respectively.
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- Pureté: 99.92%
- CAS No.: 83465-22-9
- Formule: C7H15NO5
- Masse moléculaire:193.20
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
831 μM
Compound: EB-0155
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
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[PMID: 34870992] |
In Vitro
Valiolamine inhibits α-Glucosidase (Yeast), Maltase (Porcine), isomaltase (Porcine), sucrose (Porcine) and β -Glucosidase (Almond) with IC50 values of 0.19 mM, 2.2 μM, 2.7 μM, 0.049 μM and 8.1 mM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 83465-22-9
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Appearance Solid
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Masse moléculaire 193.20
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Formule C7H15NO5
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Color White to light yellow
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SMILES
O[C@H]1[C@@](C[C@@H](N)[C@H]([C@@H]1O)O)(CO)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
H2O : 175 mg/mL (905.80 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.1760 mL | 25.8799 mL | 51.7598 mL | 129.3996 mL |
| 5 mM | 1.0352 mL | 5.1760 mL | 10.3520 mL | 25.8799 mL | |
| 10 mM | 0.5176 mL | 2.5880 mL | 5.1760 mL | 12.9400 mL | |
| 15 mM | 0.3451 mL | 1.7253 mL | 3.4507 mL | 8.6266 mL | |
| 20 mM | 0.2588 mL | 1.2940 mL | 2.5880 mL | 6.4700 mL | |
| 25 mM | 0.2070 mL | 1.0352 mL | 2.0704 mL | 5.1760 mL | |
| 30 mM | 0.1725 mL | 0.8627 mL | 1.7253 mL | 4.3133 mL | |
| 40 mM | 0.1294 mL | 0.6470 mL | 1.2940 mL | 3.2350 mL | |
| 50 mM | 0.1035 mL | 0.5176 mL | 1.0352 mL | 2.5880 mL | |
| 60 mM | 0.0863 mL | 0.4313 mL | 0.8627 mL | 2.1567 mL | |
| 80 mM | 0.0647 mL | 0.3235 mL | 0.6470 mL | 1.6175 mL | |
| 100 mM | 0.0518 mL | 0.2588 mL | 0.5176 mL | 1.2940 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Valiolamine Related Classifications
HY-131114 Related Classifications
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