VDR agonist 2
VDR agonist 2 (compound 16i) is a VDR (vitamin D receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC). VDR agonist 2 has significant anti-hepatic fibrosis effects both in vitro and in vivo.
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- CAS No.: 3052323-55-1
- Formule: C20H21F3O3
- Masse moléculaire:366.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
VDR[1].
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LX-2 | IC50 |
>30 μM
Compound: 16i
|
Cytotoxicity against human LX-2 cells by CCK-8 assay
Cytotoxicity against human LX-2 cells by CCK-8 assay
|
[PMID: 37406383] |
Chemical Information
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CAS No. 3052323-55-1
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Masse moléculaire 366.37
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Formule C20H21F3O3
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SMILES
FC(F)(CCCOC1=CC=C(/C=C/C2=CC=C(C(CO)=C2)CO)C=C1)F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)