Z-4105
Z-4105 is an orally active nootropic agent. Z-4105 reverses the amnesic effects of electroconvulsive shock (ECS) and methylazoxymethanol acetate (MAM), and improves learning and memory functions. Z-4105 enhances the activity of the brain cholinergic system without affecting other neurotransmitter systems. Z-4105 significantly alleviates neuropathic pain in rats. Z-4105 can be used in the research of neuropathic pain and brain dysfunction.
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- CAS No.: 119737-52-9
- Formule: C9H12N2O4
- Masse moléculaire:212.20
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar (male, chronic constrictive injury of the sciatic nerve model); Wistar (male, spinal nerve ligation model)[1]
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Dosage:3 mg/kg; 30 mg/kg; 300 mg/kg
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Administration:p.o.; single dose
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Result:Reduced mechanical allodynia in a dose-dependent manner.
Produced statistically significant antiallodinic effect starting at 3 mg/kg, which persisted up to 6 hours post-treatment.
Reduced mechanical allodynia in a dose-dependent manner.
Produced statistically significant antiallodinic effect starting at 3 mg/kg, which persisted up to 6 hours post-treatment.
Chemical Information
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CAS No. 119737-52-9
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Masse moléculaire 212.20
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Formule C9H12N2O4
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SMILES
O=C(CCCNC(C1=CC(C)=NO1)=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Z-4105 Related Classifications
HY-W987949 Related Classifications
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