Calcium alginate
Based on 1 Customer Validation
Calcium alginate is a biopolymer that can be used for developing oral agent-delivery systems. Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media.
For research use only. We do not sell to patients.
- CAS No.: 9005-35-0
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media. This enables the hydrogel to absorb and release aqueous solutions at certain ranges of pH values. By absorbing an aqueous solution containing a drug, an active drug release can be triggered at a specified range of pH value[2].
Calcium alginate is a biodegradable gel-transforming agent widely used for nasal packing. It can reduce pain and improve comfort[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 9005-35-0
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Appearance Solid
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Color White to light yellow
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SMILES
[Calcium alginate]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Demitri C, et al. Encapsulation of Lactobacillus kefiri in alginate microbeads using a double novel aerosol technique. Mater Sci Eng C Mater Biol Appl. 2017;77:548-555. [Content Brief]
[2]. Chengzhi Hu, et al. Electrosynthesis of magnetoresponsive microrobot for targeted drug delivery using calcium alginate. Annu Int Conf IEEE Eng Med Biol Soc. 2016;2016:2111-2114. [Content Brief]
[3]. Park DY, et al. Comparison of calcium alginate and carboxymethyl cellulose for nasal packing after endoscopic sinus surgery: a prospective, randomised, controlled single-blinded trial. Clin Otolaryngol. 2016;41(3):234-240. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)