Candesartan methyl ester
Based on 1 Customer Validation
Candesartan methyl ester (compound 14) is an antagonist for angiotensin II (AII) receptor with an IC50 of 66 nM. Candesartan methyl ester exhibits blood pressure lowering activity in rats models.
For research use only. We do not sell to patients.
- Purity: 98.13%
- CAS No.: 139481-69-9
- Formula: C25H22N6O3
- Molecular Weight:454.48
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Angiotensin Receptor Isoforms
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Biological Activity
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AT2 Receptor 66 nM (IC50) |
Chemical Information
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CAS No. 139481-69-9
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Appearance Solid
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Molecular Weight 454.48
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Formula C25H22N6O3
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Color White to off-white
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SMILES
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (220.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2003 mL | 11.0016 mL | 22.0032 mL | 55.0079 mL |
| 5 mM | 0.4401 mL | 2.2003 mL | 4.4006 mL | 11.0016 mL | |
| 10 mM | 0.2200 mL | 1.1002 mL | 2.2003 mL | 5.5008 mL | |
| 15 mM | 0.1467 mL | 0.7334 mL | 1.4669 mL | 3.6672 mL | |
| 20 mM | 0.1100 mL | 0.5501 mL | 1.1002 mL | 2.7504 mL | |
| 25 mM | 0.0880 mL | 0.4401 mL | 0.8801 mL | 2.2003 mL | |
| 30 mM | 0.0733 mL | 0.3667 mL | 0.7334 mL | 1.8336 mL | |
| 40 mM | 0.0550 mL | 0.2750 mL | 0.5501 mL | 1.3752 mL | |
| 50 mM | 0.0440 mL | 0.2200 mL | 0.4401 mL | 1.1002 mL | |
| 60 mM | 0.0367 mL | 0.1834 mL | 0.3667 mL | 0.9168 mL | |
| 80 mM | 0.0275 mL | 0.1375 mL | 0.2750 mL | 0.6876 mL | |
| 100 mM | 0.0220 mL | 0.1100 mL | 0.2200 mL | 0.5501 mL |
Candesartan methyl ester Related Classifications
HY-W098792 Related Classifications
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