Captopril EP Impurity E
Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
For research use only. We do not sell to patients.
- CAS No.: 23500-15-4
- Formula: C9H15NO3
- Molecular Weight:185.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
>250 μM
Compound: L-C1
|
Cytotoxicity against human HeLa cells incubated for 72 hrs by alamar blue cell viability assay
Cytotoxicity against human HeLa cells incubated for 72 hrs by alamar blue cell viability assay
|
[PMID: 39013490] |
Chemical Information
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CAS No. 23500-15-4
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Molecular Weight 185.22
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Formula C9H15NO3
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SMILES
O=C(O)[C@H]1N(C(C(C)C)=O)CCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268. [Content Brief]
[3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)