Carboprost methyl
15(S)-15-methyl Prostaglandin F2α methyl ester (15(S)-15-methyl PGF2α methyl ester) is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability. Hydrolysis of the methyl ester in vivo releases the biologically active 15(S)-15-methyl PGF2α, which is a potent uterine stimulant and abortifacient.
For research use only. We do not sell to patients.
- CAS No.: 35700-21-1
- Formula: C22H38O5
- Molecular Weight:382.53
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
-
HY-N0437S
Progesterone-d9Stable Isotope -
HY-B0412S
Estriol-d2Stable Isotope -
HY-B0234S1
Estrone-d2Stable Isotope -
HY-B0554S
Norethindrone-d6Stable Isotope -
HY-113246
15-keto-Prostaglandin F2aPGF2α Metabolite -
HY-106077
MeteneprostCervical Dilator -
HY-114841
ONO 207 -
HY-118754
13,14-Dihydro-15-keto PGF1αPGF1α Metabolite -
HY-131617
Prostaglandin F2α 1,11-lactoneProstaglandin -
HY-137412
PGF2α 1,15-lactonePGF2α Internal ester -
HY-116843
(15S)-15-Methylprostaglandin E2PGE2 Analog -
HY-157002
Prostaglandin E2 isopropyl esterPGE2 Precursor
Biological Activity
Description
Chemical Information
-
CAS No. 35700-21-1
-
Molecular Weight 382.53
-
Formula C22H38O5
-
SMILES
CCCCC[C@](C)(O)/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C/C=C\CCCC(OC)=O
-
Synonyms
Methyl carboprost; 15(S)-15-Methyl PGF2α methyl ester; U-36384
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Transepithelial/transendothelial electrical resistance assay
TEER measures electrical resistance across epithelial or endothelial monolayers cultured on permeable supports, and the readout reflects ionic conductance through the cell barrier, especially the paracellular pathway regulated by junctional integrity. TEER can be measured without destroying the monolayer and is commonly used before or during transport, permeability, barrier-disruption, and barrier-maturation experiments. TEER values are influenced by biological maturation and technical conditions; reported factors include temperature, medium formulation, passage number, electrode geometry, membrane properties, and junctional length during early monolayer maturation. Therefore, TEER should be interpreted with blank-insert subtraction, area normalization, repeated readings, and, when possible, orthogonal barrier readouts such as FITC-dextran flux or tight-junction staining.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carboprost methyl Related Classifications
HY-128550 Related Classifications
Powered by Bioz