101-17-7
Chemical Structure
3-Chlorodiphenylamine
- CAS. Nr.: 101-17-7
- Formula:C12H10ClN
- Molecular Weight:203.67
IUPAC Name: 3-chloro-N-phenylaniline
InChIKey: OHHIBZKYXJDQEU-UHFFFAOYSA-N
SMILES: ClC1=CC(NC2=CC=CC=C2)=CC=C1
Biological Activity: 3-Chlorodiphenylamine is a high affinity Ca2+ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) (Kd=6 µM). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca2+-sensitizing compounds due to its small size, and can be used for systolic heart failure research[1].
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3-Chlorodiphenylamine | 98.74% | 3-Chlorodiphenylamine is a high affinity Ca2+ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) (Kd=6 µM). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca2+-sensitizing compounds due to its small size, and can be used for systolic heart failure research. | ||||||||||||||||||||
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Keywords
