1019169-83-5
1019169-83-5
Chemical Structure
SQLE-IN-1
- CAS No.: 1019169-83-5
- Formula:C24H21F2N5O2S
- Molecular Weight:481.52
InChIKey: JVHLHGQTUDIPMK-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(F)C=C1F)(NC2=CC=C(NC3=NC(C)=NC(NC4=CC=C(C)C=C4)=C3)C=C2)=O
Biological Activity: SQLE-IN-1 (compound 19) is a squalene epoxidase (SQLE) inhibitor. SQLE-IN-1 inhibits the proliferation and migration of Huh7 cells. SQLE-IN-1 inhibits the cell cholesterol generation. SQLE-IN-1 increases the expression of PTEN and inhibits PI3K and AKT[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SQLE-IN-1 | 99.21% | SQLE-IN-1 (compound 19) is a squalene epoxidase (SQLE) inhibitor. SQLE-IN-1 inhibits the proliferation and migration of Huh7 cells. SQLE-IN-1 inhibits the cell cholesterol generation. SQLE-IN-1 increases the expression of PTEN and inhibits PI3K and AKT. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.55
HY-182378Vps34-IN-5 -
Similarity Score 0.53
HY-162671BuChE-IN-12 -
Similarity Score 0.52
HY-147955CAI/II-IN-5 -
Similarity Score 0.51
HY-147952AChE-IN-20 -
Similarity Score 0.51
HY-13962SGI-1027 -
Similarity Score 0.51
HY-160457FABP4/5-IN-5 -
Similarity Score 0.51
HY-136538LQZ-7I -
Similarity Score 0.51
HY-W722305N1,N4-Di-P-tolylbenzene-1,4-diamine -
Similarity Score 0.51
HY-147667α-Synuclein inhibitor 5 -
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