102-76-1
Chemical Structure
Triacetin
Synonym(s): Glyceryl triacetate; 1,2,3-Triacetoxypropane
- CAS. Nr.: 102-76-1
- Formula:C9H14O6
- Molecular Weight:218.20
IUPAC Name: propane-1,2,3-triyl triacetate
InChIKey: URAYPUMNDPQOKB-UHFFFAOYSA-N
SMILES: CC(OCC(OC(C)=O)COC(C)=O)=O
Biological Activity: Triacetin (Glyceryl triacetate) is a synthetic compound that is a triester of glycerol and acetic acid, orally active. Triacetin increases acetate bioavailability in glioma cells. Triacetin induces glioma cell growth arrest and Apoptosis. Triacetin freely crosses the blood brain barrier/plasma membrane. Triacetin increases histone acetylation and enhances Temozolomide (HY-17364) (TMZ) chemotherapeutic efficacy [1][2].
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Triacetin | 99.87% | Triacetin (Glyceryl triacetate) is a synthetic compound that is a triester of glycerol and acetic acid, orally active. Triacetin increases acetate bioavailability in glioma cells. Triacetin induces glioma cell growth arrest and Apoptosis. Triacetin freely crosses the blood brain barrier/plasma membrane. Triacetin increases histone acetylation and enhances Temozolomide (HY-17364) (TMZ) chemotherapeutic efficacy . | ||||||||||||||||||||
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Triacetin (Standard) | 99.91% | Triacetin (Standard) is the analytical standard of Triacetin. This product is intended for research and analytical applications. Triacetin is a synthetic compound that is a triester of glycerol and acetic acid. | ||||||||||||||||||||
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Triacetin-d5 | Triacetin-d5 is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin. | |||||||||||||||||||||
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Triacetin-d9 | Glyceryl Triacetate-d9 is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin. | |||||||||||||||||||||
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References
- [1]. Tsen AR, et al. Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. Int J Cancer. 2014 Mar 15;134(6):1300-10. [Content Brief]
- [2]. Mekala JR, et al. N-acetyl l-aspartate and Triacetin modulate tumor suppressor MicroRNA and class I and II HDAC gene expression induce apoptosis in Glioblastoma cancer cells in vitro. Life Sci. 2021 Dec 1;286:120024. [Content Brief]
