102-76-1
102-76-1
Chemical Structure
Triacetin
Synonym(s): Glyceryl triacetate; 1,2,3-Triacetoxypropane
- No. CAS: 102-76-1
- Formula:C9H14O6
- Molecular Weight:218.20
IUPAC Name: propane-1,2,3-triyl triacetate
InChIKey: URAYPUMNDPQOKB-UHFFFAOYSA-N
SMILES: CC(OCC(OC(C)=O)COC(C)=O)=O
Biological Activity: Triacetin (Glyceryl triacetate) is a synthetic compound that is a triester of glycerol and acetic acid, orally active. Triacetin increases acetate bioavailability in glioma cells. Triacetin induces glioma cell growth arrest and Apoptosis. Triacetin freely crosses the blood brain barrier/plasma membrane. Triacetin increases histone acetylation and enhances Temozolomide (HY-17364) (TMZ) chemotherapeutic efficacy [1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Triacetin | 99.87% | Triacetin (Glyceryl triacetate) is a synthetic compound that is a triester of glycerol and acetic acid, orally active. Triacetin increases acetate bioavailability in glioma cells. Triacetin induces glioma cell growth arrest and Apoptosis. Triacetin freely crosses the blood brain barrier/plasma membrane. Triacetin increases histone acetylation and enhances Temozolomide (HY-17364) (TMZ) chemotherapeutic efficacy . | ||||||||||||||||||||
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Triacetin (Standard) | 99.91% | Triacetin (Standard) is the analytical standard of Triacetin. This product is intended for research and analytical applications. Triacetin is a synthetic compound that is a triester of glycerol and acetic acid. | ||||||||||||||||||||
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Triacetin-d5 | Triacetin-d5 is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin. | |||||||||||||||||||||
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Triacetin-d9 | Glyceryl Triacetate-d9 is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin. | |||||||||||||||||||||
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mPEG-PLGA (21500-26500) | 95.0% | MPEG-PLGA (21500-26500) is a biodegradable amphipathic polymeric nanocarrier of poly (lactic-co-glycolic acid)-block-poly (ethylene glycol) (PLGA-PEG-Mal) that allows covalent modification of functional molecules. MPEG-PLGA (21500-26500) modified with Angiopep-2 can cross the blood-brain barrier and exhibits targeting selectivity for glioblastoma cells. MPEG-PLGA (21500-26500) can capture tumor-derived protein antigens, and exerts immunomodulatory effects when conjugated with anti-OX40 antibody; when used in combination with A2-CL/Dbait nanoparticles and radiotherapy, it prolongs survival time and reduces tumor volume in glioblastoma mouse models. MPEG-PLGA (21500-26500) can be used for studies related to bacterial wound infections and glioblastoma. | ||||||||||||||||||||
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Diethylene glycol diacetate | Diethylene glycol diacetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Propane-1,2-diyl diacetate (Standard) | ≥98% | Propane-1,2-diyl diacetate (Standard) is the analytical standard of Propane-1,2-diyl diacetate. This product is intended for research and analytical applications. | ||||||||||||||||||||
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1-Methoxy-2-propyl acetate | 99.97% | 1-Methoxy-2-propyl acetate is a volatile ester compound found in chocolate made from fermented cocoa beans. 1-Methoxy-2-propyl acetate serves as a hydrolysis substrate for esterases in blood, liver, lung, and nasal mucosa, and is rapidly hydrolyzed to propylene glycol monomethyl ether and acetic acid. 1-Methoxy-2-propyl acetate is proposed as a candidate urinary biomarker for dairy product intake. 1-Methoxy-2-propyl acetate can serve as a solvent and is applied in the electronic-grade semiconductor industry. 1-Methoxy-2-propyl acetate can be used in research related to nephropathy, hepatomegaly, and nasal irritation. | ||||||||||||||||||||
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1,2-Diacetylglycerol | 1,2-Diacetylglycerol is mainly used as a plasticizer, emulsifier and stabilizer. | |||||||||||||||||||||
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2-Methylbutyl acetate-13C2 | 2-Methylbutyl acetate-13C2 is 13C labeled 2-Methylbutyl acetate. | |||||||||||||||||||||
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2,4-Diacetoxypentane | 2,4-Diacetoxypentane is an active ingredient that can be extracted from cantaloupe. 2,4-Diacetoxypentane is an ester compound with volatility. | |||||||||||||||||||||
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Diethyl succinate | 98.0% | Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings. | ||||||||||||||||||||
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Diethyl succinate-13C4 | Diethyl succinate-13C4 is the 13C labeled Diethyl succinate. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring. | |||||||||||||||||||||
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References
- [1]. Tsen AR, et al. Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. Int J Cancer. 2014 Mar 15;134(6):1300-10. [Content Brief]
- [2]. Mekala JR, et al. N-acetyl l-aspartate and Triacetin modulate tumor suppressor MicroRNA and class I and II HDAC gene expression induce apoptosis in Glioblastoma cancer cells in vitro. Life Sci. 2021 Dec 1;286:120024. [Content Brief]
