104155-89-7
Chemical Structure
FL113
- CAS 番号: 104155-89-7
- Formula:C21H16N2O6
- Molecular Weight:392.37
IUPAC Name: 7-ethyl-7-hydroxy-10,13-dihydro-11H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H)-dione
InChIKey: RPFYDENHBPRCTN-UHFFFAOYSA-N
SMILES: O=C1OCC=2C(=O)N3C(=CC2C1(O)CC)C=4N=C5C=C6OCOC6=CC5=CC4C3
Biological Activity: FL113 is a racemate of FL118 (HY-12486). FL113 is less effective than FL118 in inhibiting the expression of Survivin, Mcl-1, XIAP, and cIAP2. FL113 exhibits weaker antitumor activity than FL118 in colon tumor xenograft models. FL113 can be used for research on colon cancer and head and neck cancer[1].
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FL113 | FL113 is a racemate of FL118 (HY-12486). FL113 is less effective than FL118 in inhibiting the expression of Survivin, Mcl-1, XIAP, and cIAP2. FL113 exhibits weaker antitumor activity than FL118 in colon tumor xenograft models. FL113 can be used for research on colon cancer and head and neck cancer. | |||||||||||||||||||||
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