105-60-2
105-60-2
Chemical Structure
Azepan-2-one
- CAS No.: 105-60-2
- Formula:C6H11NO
- Molecular Weight:113.16
IUPAC Name: azepan-2-one
InChIKey: JBKVHLHDHHXQEQ-UHFFFAOYSA-N
SMILES: O=C1NCCCCC1
Biological Activity: Azepan-2-one is a seven-membered lactam (cyclic amide) scaffold found in the natural product Capuramycin. It serves as the core structural component required for the CB2 agonist activity of 4-(1,2,4-oxadiazol-5-yl) azepan-2-one derivatives. Azepan-2-one is used in tuberculosis research[1][2].
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Azepan-2-one | 99.97% | Azepan-2-one is a seven-membered lactam (cyclic amide) scaffold found in the natural product Capuramycin. It serves as the core structural component required for the CB2 agonist activity of 4-(1,2,4-oxadiazol-5-yl) azepan-2-one derivatives. Azepan-2-one is used in tuberculosis research. | ||||||||||||||||||||
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Azepan-2-one (Standard) | ≥98% | Azepan-2-one (Standard) is the analytical standard of Azepan-2-one (HY-W010542). This product is intended for research and analytical applications. Azepan-2-one is a seven-membered lactam (cyclic amide) scaffold found in the natural product Capuramycin. It serves as the core structural component required for the CB2 agonist activity of 4-(1,2,4-oxadiazol-5-yl) azepan-2-one derivatives. Azepan-2-one is used in tuberculosis research. | ||||||||||||||||||||
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Azepan-2-one-d10 | 99.8% | Azepan-2-one-d10 is the deuterated-labeled Azepan-2-one (HY-W010542). Azepan-2-one is a seven-membered lactam (cyclic amide) scaffold found in the natural product Capuramycin. It serves as the core structural component required for the CB2 agonist activity of 4-(1,2,4-oxadiazol-5-yl) azepan-2-one derivatives. Azepan-2-one is used in tuberculosis research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.93
HY-W042193R2-Piperidone (Standard) -
Similarity Score 0.79
HY-W0018454-Azepanone hydrochloride -
Similarity Score 0.78
HY-41240(R)-3-Aminoazepan-2-one -
Similarity Score 0.78
HY-W002297(S)-3-Aminoazepan-2-one -
Similarity Score 0.78
![2-Azaspiro[4.5]decan-3-one (Standard) Chemical Structure](//file.medchemexpress.com/product_pic/hy-w039179r.gif)
HY-W039179R2-Azaspiro[4.5]decan-3-one (Standard) -
Similarity Score 0.77
HY-W015366(S)-3-Amino-2-oxo-azepane hydrochloride -
Similarity Score 0.75
HY-W002860Cycloheptane-1,3-dione -
Similarity Score 0.75
HY-W165232N-Methylvalerolactam -
Similarity Score 0.74
HY-I0466Glutarimide -
Explore the MedChemAI to find more analogs
![2-Azaspiro[4.5]decan-3-one (Standard) Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w039179r.gif)
References
- [1]. Hotoda H, et al. Synthesis and antimycobacterial activity of capuramycin analogues. Part 1: substitution of the azepan-2-one moiety of capuramycin. Bioorganic & medicinal chemistry letters. 2003 Sep 01;13(17):2829-32.
- [2]. Nan J, et al. Discovery of 4-(1,2,4-Oxadiazol-5-yl)azepan-2-one Derivatives as a New Class of Cannabinoid Type 2 Receptor Agonists for the Treatment of Inflammatory Pain. Journal of medicinal chemistry. 2023 Mar 09;66(5):3460-3483.
