109844-92-0
109844-92-0
Chemical Structure
LCS3
- CAS No.: 109844-92-0
- Formula:C11H7ClN2O4
- Molecular Weight:266.64
IUPAC Name: N-(4-chlorophenyl)-5-nitrofuran-2-carboxamide
InChIKey: JDBZJNUHQINERI-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(Cl)C=C2
Biological Activity: LCS3 is a reversible and uncompetitive glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) inhibitor (IC50=3.3 µM and 3.8 µM, respectively). LCS3 shows anti-tumor activity, and induces apoptosis. LCS3 can be used in lung adenocarcinoma (LUAD) research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LCS3 | 99.43% | LCS3 is a reversible and uncompetitive glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) inhibitor (IC50=3.3 µM and 3.8 µM, respectively). LCS3 shows anti-tumor activity, and induces apoptosis. LCS3 can be used in lung adenocarcinoma (LUAD) research. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.88
HY-112906C-176 -
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HY-168676STING ligand-2 -
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HY-138682STING-IN-2 -
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HY-138683STING-IN-3 -
Similarity Score 0.71
HY-47709STING ligand-3 -
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HY-120284CCCI-01 -
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HY-151514Antituberculosis agent-5 -
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HY-W224634HSF1-IN-2 -
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HY-118639CP-74006 -
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