1. Immunology/Inflammation
  2. STING
  3. STING-IN-3

STING-IN-3 

Cat. No.: HY-138683 Purity: 99.30%
Handling Instructions

STING-IN-3 is an inhibitor of stimulator of interferon genes (STING). STING-IN-3 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING.

For research use only. We do not sell to patients.

STING-IN-3 Chemical Structure

STING-IN-3 Chemical Structure

CAS No. : 2244881-69-2

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
25 mg USD 100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 160 In-stock
Estimated Time of Arrival: December 31
100 mg USD 250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

STING-IN-3 is an inhibitor of stimulator of interferon genes (STING). STING-IN-3 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING[1].

IC50 & Target

STING[1]

In Vitro

STING-IN-3 (0.02-2 μM) inhibits hsSTING and mmSTING, mediated IFNβ reporter activity in HEK293 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

316.35

Formula

C₁₇H₂₀N₂O₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (790.26 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1611 mL 15.8053 mL 31.6106 mL
5 mM 0.6322 mL 3.1611 mL 6.3221 mL
10 mM 0.3161 mL 1.5805 mL 3.1611 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
STING-IN-3
Cat. No.:
HY-138683
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