1. Immunology/Inflammation
  2. STING
  3. STING-IN-2

STING-IN-2 

Cat. No.: HY-138682 Purity: 98.39%
Handling Instructions

STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research.

For research use only. We do not sell to patients.

STING-IN-2 Chemical Structure

STING-IN-2 Chemical Structure

CAS No. : 346691-38-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
25 mg USD 100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 160 In-stock
Estimated Time of Arrival: December 31
100 mg USD 250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research[1].

In Vitro

THP-1 cells are pretreated with STING-IN-2 (C-170; 0.5 μM) and stimulated with cGAMP. STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

288.30

Formula

C₁₅H₁₆N₂O₄

CAS No.
SMILES

O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCC)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Keywords:

STING-IN-2STINGStimulator of Interferon GenesTMEM173MITAERISMPYSpalmitoylationautoinflammatorycGAMPIFNB1p-TBK1TNFInhibitorinhibitorinhibit

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STING-IN-2
Cat. No.:
HY-138682
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