11013-97-1
Chemical Structure
Methyl-Hesperidin
- CAS No.: 11013-97-1
- Formula:C29H36O15
- Molecular Weight:624.59
IUPAC Name: (S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one compound with (S)-2-(3-hydroxy-4-methoxyphenyl)-5-methoxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one (1:1)
InChIKey: ASXRKTOFMMXIET-YIZBCMEYSA-N
SMILES: O=C1C[C@@H](C2=CC=C(OC)C(O)=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)O4)O)O)O)=CC(OC)=C13.O=C6C[C@@H](C7=CC=C(OC)C(OC)=C7)OC8=CC(O[C@H]9[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]%10[C@@H]([C@@H]([C@H]([C@H](C)O%10)O)O)O)O9)O)O)O)=CC(O)=C68
Biological Activity: Methyl-Hesperidin is a glycoside compound. Methyl-Hesperidin has hypotensive, coronary dilating, smooth muscle relaxing, capillary stabilizing, choleretic, and anti-ulcer activities. Methyl-Hesperidin act as a competitive substrate to inhibit HIV-1 reverse transcriptase activity. Methyl-Hesperidin potentiates coronary dilating actions of adenine nucleotides and 3'-AMP, enhances depressant action on isolated atria, and prolongs adenosine- and ATP-induced heart block in guinea pigs[1][2].
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Methyl-Hesperidin | 99.70% | Methyl-Hesperidin is a glycoside compound. Methyl-Hesperidin has hypotensive, coronary dilating, smooth muscle relaxing, capillary stabilizing, choleretic, and anti-ulcer activities. Methyl-Hesperidin act as a competitive substrate to inhibit HIV-1 reverse transcriptase activity. Methyl-Hesperidin potentiates coronary dilating actions of adenine nucleotides and 3'-AMP, enhances depressant action on isolated atria, and prolongs adenosine- and ATP-induced heart block in guinea pigs. | ||||||||||||||||||||
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Methyl-Hesperidin (Standard) | ≥98% | Methyl-Hesperidin (Standard) is the analytical standard of Methyl-Hesperidin (HY-N0165). This product is intended for research and analytical applications. Methyl-Hesperidin is a glycoside compound. Methyl-Hesperidin has hypotensive, coronary dilating, smooth muscle relaxing, capillary stabilizing, choleretic, and anti-ulcer activities. Methyl-Hesperidin act as a competitive substrate to inhibit HIV-1 reverse transcriptase activity. Methyl-Hesperidin potentiates coronary dilating actions of adenine nucleotides and 3'-AMP, enhances depressant action on isolated atria, and prolongs adenosine- and ATP-induced heart block in guinea pigs. | ||||||||||||||||||||
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References
- [1]. Riza H, et al. Docking study of methyl hesperidin as nucleoside reverse transcriptase inhibitor[J]. Int. J. Pharm. Pharm. Sci, 2018, 10: 85.
- [2]. KIKUCHI K, et al. The potentiation of the coronary dilating and the cardiac action of adenosine or adenine nucleotides by methylhesperidin[J]. The Japanese Journal of Pharmacology, 1966, 16(2): 224-225.
