111-20-6
111-20-6
Chemical Structure
Decanedioic acid
Synonym(s): Sebacic acid
- CAS No.: 111-20-6
- Formula:C10H18O4
- Molecular Weight:202.25
IUPAC Name: decanedioic acid
InChIKey: CXMXRPHRNRROMY-UHFFFAOYSA-N
SMILES: O=C(O)CCCCCCCCC(O)=O
Biological Activity: Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Decanedioic acid | 99.97% | Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency. | ||||||||||||||||||||
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Decanedioic acid (Standard) | ≥98% | Decanedioic acid (Standard) is the analytical standard of Decanedioic acid (HY-W014787). This product is intended for research and analytical applications. Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency. | ||||||||||||||||||||
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Decanedioic acid-13C2 | Decanedioic acid-13C2 (Sebacic acid-13C2) is the 13C-labeled Decanedioic acid (HY-W014787). Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency. | |||||||||||||||||||||
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Decanedioic acid-d16 | Decanedioic acid-d16 is the deuterated-labeled Decanedioic acid (HY-W014787). Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.96
HY-W014125RUndecanedioic acid (Standard) -
Similarity Score 0.96
HY-B0704RAzelaic acid (Standard) -
Similarity Score 0.92
HY-W015300Suberic acid -
Similarity Score 0.91
HY-W969553Sebacamic acid -
Similarity Score 0.89
HY-Y1139Pimelic acid -
Similarity Score 0.89
HY-W150022Sebacic acid monomethyl ester -
Similarity Score 0.87
HY-W0100479-Hydroxynonanoic acid -
Similarity Score 0.86
HY-W5100329-Ethoxy-9-oxononanoic acid -
Similarity Score 0.86
HY-W098052R9-Methoxy-9-oxononanoic acid (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Bertuzzi A, et al. Sebacic acid binding to human plasma albumin. Biochem Pharmacol. 1993 Feb 9;45(3):697-702. [Content Brief]
- [2]. Angelini G, et al. Dodecanedioic acid prevents and reverses metabolic-associated liver disease and obesity and ameliorates liver fibrosis in a rodent model of diet-induced obesity. FASEB J. 2024 Nov 30;38(22):e70202. [Content Brief]
- [3]. Salinari S, et al. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetic subjects. American Journal of Physiology-Endocrinology and Metabolism, 2006, 291(5): E1051-E1058.
