119152-50-0
119152-50-0
Chemical Structure
Glychionide A
- CAS No.: 119152-50-0
- Formula:C21H18O11
- Molecular Weight:446.36
IUPAC Name: (2S,3S,4S,5R,6S)-6-((5,8-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChIKey: MOFOLNOWFPVLGZ-BHWDSYMASA-N
SMILES: O=C1C(C(OC(C2=CC=CC=C2)=C1)=C3O)=C(C=C3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)O
Biological Activity: Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer[1][2].
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Glychionide A | 99.47% | Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer. | ||||||||||||||||||||
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Glychionide A (Standard) | ≥98% | Glychionide A (Standard) is the analytical standard of Glychionide A (HY-N8034). This product is intended for research and analytical applications. Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-N0399Wogonoside -
Similarity Score 0.87
HY-N12394Norwogonin-8-O-glucuronide -
Similarity Score 0.86
HY-N0197Baicalin -
Similarity Score 0.86
HY-N17537Norwogonin-7-O-glucoside -
Similarity Score 0.83
HY-N114885,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb -
Similarity Score 0.82
HY-N127935,6-Dihydroxy-8-methoxyflavone-7-O-glucuronide -
Similarity Score 0.82
HY-N7035Wogonin 7-O-beta-D-glucuronide methyl ester -
Similarity Score 0.81
HY-N2481ROroxylin A-7-O-glucuronide (Standard) -
Similarity Score 0.80
HY-N2376RChrysin-7-O-glucuronide (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Li JR, et, al. Two new compounds from Glycyrrhiza glabra. J Asian Nat Prod Res. 2005 Aug;7(4):677-80. [Content Brief]
- [2]. Yu L, et, al. Antitumor Effects of Glychionide-A Flavonoid in Human Pancreatic Carcinoma Cells Are Mediated by Activation of Apoptotic and Autophagic Pathways, Cell Cycle Arrest, and Disruption of Mitochondrial Membrane Potential. Med Sci Monit. 2019 Feb 3;25:962-969. [Content Brief]
