1215071-00-3
1215071-00-3
Chemical Structure
Donepezil-d7
Synonym(s): E2020-d7 free base
- CAS No.: 1215071-00-3
- Formula:C24H22D7NO3
- Molecular Weight:386.54
InChIKey: ADEBPBSSDYVVLD-UOOROTEOSA-N
SMILES: O=C1C(CC2CCN(C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])([2H])[2H])CC2)CC4=C1C=C(OC)C(OC)=C4
Biological Activity: Donepezil-d7 (E2020-d7 (free base)) is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].
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Donepezil-d7 | Donepezil-d7 (E2020-d7 (free base)) is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. | |||||||||||||||||||||
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Donepezil (Standard) | ≥98% | Donepezil (Standard) is the analytical standard of Donepezil. This product is intended for research and analytical applications. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. | ||||||||||||||||||||
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Donepezil-d4 | Donepezil-d4 (E2020-d4 (free base)) is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. | |||||||||||||||||||||
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Donepezil-d5 | 99.30% | Donepezil-d5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. | ||||||||||||||||||||
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Donepezil | 99.82% | Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-136838(R)-Donepezil -
Similarity Score 1.00
HY-14566A(S)-Donepezil -
Similarity Score 0.98
HY-B0034SDonepezil-d5 hydrochloride -
Similarity Score 0.98
HY-B0034Donepezil Hydrochloride -
Similarity Score 0.90
HY-133926S5-O-Desmethyl donepezil-d5 -
Similarity Score 0.90
HY-133925S6-O-Desmethyl donepezil-d5 -
Similarity Score 0.89
HY-1339265-O-Desmethyl donepezil -
Similarity Score 0.89
HY-1339256-O-Desmethyl donepezil -
Similarity Score 0.81
HY-134137Donepezil N-oxide -
Explore the MedChemAI to find more analogs
