1217809-61-4
1217809-61-4
Chemical Structure
Ivabradine-d3 hydrochloride
- CAS No.: 1217809-61-4
- Formula:C27H34D3ClN2O5
- Molecular Weight:508.06
IUPAC Name: (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl-d3)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride
InChIKey: HLUKNZUABFFNQS-AFMQDYKRSA-N
SMILES: [H]Cl.COC1=C(OC)C=C(CCN(CCCN(C([2H])([2H])[2H])C[C@@H]2C(C=C(OC)C(OC)=C3)=C3C2)C(C4)=O)C4=C1
Biological Activity: Ivabradine-d3 (hydrochloride) is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.
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Ivabradine-d3 hydrochloride | Ivabradine-d3 (hydrochloride) is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent. | |||||||||||||||||||||
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Ivabradine hydrochloride (Standard) | ≥98% | Ivabradine hydrochloride (Standard) is the analytical standard of Ivabradine hydrochloride. This product is intended for research and analytical applications. Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity. | ||||||||||||||||||||
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Ivabradine-d6 hydrochloride | 96.26% | Ivabradine-d6 hydrochloride is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent. | ||||||||||||||||||||
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Ivabradine hydrochloride | 99.71% | Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity. | ||||||||||||||||||||
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