127785-64-2
127785-64-2
Chemical Structure
Aureobasidin A
Synonym(s): Basifungin
- CAS No.: 127785-64-2
- Formula:C60H92N8O11
- Molecular Weight:1101.42
InChIKey: RLMLFADXHJLPSQ-QKCBWMAHSA-N
SMILES: O=C([C@@H](N(C([C@@H](NC([C@@H](N(C([C@@](OC1=O)([H])[C@H](C)CC)=O)C)C(C)C)=O)CC2=CC=CC=C2)=O)C)CC3=CC=CC=C3)N(CCC4)[C@]4([H])C(N[C@@](C(N([C@H](C(N[C@H](C(N([C@H]1C(C)(O)C)C)=O)CC(C)C)=O)C(C)C)C)=O)([H])[C@H](C)CC)=O
Biological Activity: Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aureobasidin A | 99.31% | Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity. | ||||||||||||||||||||
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References
- [1]. Zheng L, et al. Chromosome 1 trisomy confers resistance to aureobasidin A in Candida albicans. Front Microbiol. 2023 Mar 17;14:1128160. [Content Brief]
- [2]. Alqaisi AQI, et al. The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis. Parasitology. 2018 Feb;145(2):148-155. [Content Brief]
- [3]. Takesako K, et al. Biological properties of aureobasidin A, a cyclic depsipeptide antifungal antibiotic. J Antibiot (Tokyo). 1993 Sep;46(9):1414-20. [Content Brief]
