129244-66-2

Hoechst 33258 analog 6 Chemical Structure
129244-66-2

Chemical Structure

Hoechst 33258 analog 6

  • CAS No.: 129244-66-2
  • Formula:C33H40N6O
  • Molecular Weight:536.71

IUPAC Name: 2,6-di-tert-butyl-4-(6-(4-methylpiperazin-1-yl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenol

InChIKey: LXRWWFIBSFWADZ-UHFFFAOYSA-N

SMILES: OC1=C(C(C)(C)C)C=C(C2=NC3=CC=C(C4=NC5=CC=C(N6CCN(C)CC6)C=C5N4)C=C3N2)C=C1C(C)(C)C

Biological Activity: Hoechst 33258 analog 6 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution (Ex/Em = 356/451 nm)[1].

Cat. No. Product Name Purity Description Pricing
HY-15631 		Hoechst 33258 analog 6 99.21% Hoechst 33258 analog 6 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution (Ex/Em = 356/451 nm).
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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