1346547-00-9
1346547-00-9
Chemical Structure
GSK583
- CAS No.: 1346547-00-9
- Formula:C20H19FN4O2S
- Molecular Weight:398.45
IUPAC Name: 6-(tert-butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine
InChIKey: XLOGLWKOHPIJLV-UHFFFAOYSA-N
SMILES: FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
Biological Activity: GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.
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GSK583 | 99.93% | GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM. | ||||||||||||||||||||
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GSK583 (Standard) | ≥98% | GSK583 (Standard) is the analytical standard of GSK583 (HY-100339). This product is intended for research and analytical applications. GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM. | ||||||||||||||||||||
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Keywords
