RIPK2 ligand 3
Based on 1 Customer Validation
RIPK2 ligand 3 is a RIPK2 ligand and can be used for the synthesis of PROTACs, such as PROTAC RIPK degrader-2 (HY-111866).
For research use only. We do not sell to patients.
- Purity : 99.26%
- CAS No.: 2027561-86-8
- Formula: C20H19N3O3S2
- Molecular Weight:413.51
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Description
IC50 & Target
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RIPK2 |
Chemical Information
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CAS No. 2027561-86-8
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Appearance Solid
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Molecular Weight 413.51
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Formula C20H19N3O3S2
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SMILES
O=S(C1=C(O)C=C2N=CC=C(NC3=CC=C(SC=N4)C4=C3)C2=C1)(C(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 135 mg/mL (326.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (299 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4183 mL | 12.0916 mL | 24.1832 mL | 60.4580 mL |
| 5 mM | 0.4837 mL | 2.4183 mL | 4.8366 mL | 12.0916 mL | |
| 10 mM | 0.2418 mL | 1.2092 mL | 2.4183 mL | 6.0458 mL | |
| 15 mM | 0.1612 mL | 0.8061 mL | 1.6122 mL | 4.0305 mL | |
| 20 mM | 0.1209 mL | 0.6046 mL | 1.2092 mL | 3.0229 mL | |
| 25 mM | 0.0967 mL | 0.4837 mL | 0.9673 mL | 2.4183 mL | |
| 30 mM | 0.0806 mL | 0.4031 mL | 0.8061 mL | 2.0153 mL | |
| 40 mM | 0.0605 mL | 0.3023 mL | 0.6046 mL | 1.5115 mL | |
| 50 mM | 0.0484 mL | 0.2418 mL | 0.4837 mL | 1.2092 mL | |
| 60 mM | 0.0403 mL | 0.2015 mL | 0.4031 mL | 1.0076 mL | |
| 80 mM | 0.0302 mL | 0.1511 mL | 0.3023 mL | 0.7557 mL | |
| 100 mM | 0.0242 mL | 0.1209 mL | 0.2418 mL | 0.6046 mL |