1374984-75-4
Chemical Structure
BVT173187
- CAS No.: 1374984-75-4
- Formula:C14H10Cl3NO2
- Molecular Weight:330.59
IUPAC Name: 3,5-dichloro-N-(2-chloro-5-methylphenyl)-2-hydroxybenzamide
InChIKey: UCOQCHLODZCXRH-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=CC(Cl)=C1O)NC2=CC(C)=CC=C2Cl
Biological Activity: BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling.
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BVT173187 | 99.97% | BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling. | ||||||||||||||||||||
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Keywords
