1374984-75-4

BVT173187 Chemical Structure
1374984-75-4

Chemical Structure

BVT173187

  • CAS. Nr.: 1374984-75-4
  • Formula:C14H10Cl3NO2
  • Molecular Weight:330.59

IUPAC Name: 3,5-dichloro-N-(2-chloro-5-methylphenyl)-2-hydroxybenzamide

InChIKey: UCOQCHLODZCXRH-UHFFFAOYSA-N

SMILES: O=C(C1=CC(Cl)=CC(Cl)=C1O)NC2=CC(C)=CC=C2Cl

Biological Activity: BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling.

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-117971 		BVT173187 99.97% BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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