BVT173187
Based on 1 Customer Validation
BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 1374984-75-4
- Formula: C14H10Cl3NO2
- Molecular Weight:330.59
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 1374984-75-4
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Appearance Solid
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Molecular Weight 330.59
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Formula C14H10Cl3NO2
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Color White to off-white
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SMILES
O=C(C1=CC(Cl)=CC(Cl)=C1O)NC2=CC(C)=CC=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (302.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.0249 mL | 15.1245 mL | 30.2489 mL | 75.6224 mL |
| 5 mM | 0.6050 mL | 3.0249 mL | 6.0498 mL | 15.1245 mL | |
| 10 mM | 0.3025 mL | 1.5124 mL | 3.0249 mL | 7.5622 mL | |
| 15 mM | 0.2017 mL | 1.0083 mL | 2.0166 mL | 5.0415 mL | |
| 20 mM | 0.1512 mL | 0.7562 mL | 1.5124 mL | 3.7811 mL | |
| 25 mM | 0.1210 mL | 0.6050 mL | 1.2100 mL | 3.0249 mL | |
| 30 mM | 0.1008 mL | 0.5041 mL | 1.0083 mL | 2.5207 mL | |
| 40 mM | 0.0756 mL | 0.3781 mL | 0.7562 mL | 1.8906 mL | |
| 50 mM | 0.0605 mL | 0.3025 mL | 0.6050 mL | 1.5124 mL | |
| 60 mM | 0.0504 mL | 0.2521 mL | 0.5041 mL | 1.2604 mL | |
| 80 mM | 0.0378 mL | 0.1891 mL | 0.3781 mL | 0.9453 mL | |
| 100 mM | 0.0302 mL | 0.1512 mL | 0.3025 mL | 0.7562 mL |
BVT173187 Related Classifications
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