1380716-06-2
Chemical Structure
ML198
- CAS No.: 1380716-06-2
- Formula:C17H14N4O
- Molecular Weight:290.32
IUPAC Name: N-(4-ethynylphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKey: HVZPJBKUFRREQC-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1)C#C)C2=C3N=C(C=C(N3N=C2)C)C
Biological Activity: ML198 is a glucocerebrosidase (GCase) modulator with an EC50 of 0.4 μM. ML198 is an activator and non-inhibitory chaperone of glucocerebrosidase. ML198 can be used for the research of Gaucher disease[1]. ML198 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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ML198 | 98.0% | ML198 is a glucocerebrosidase (GCase) modulator with an EC50 of 0.4 μM. ML198 is an activator and non-inhibitory chaperone of glucocerebrosidase. ML198 can be used for the research of Gaucher disease. ML198 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
