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Cat. No.: HY-169568

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EGFR-IN-147

EGFR-IN-147 (compound ID-5841161) is a potent inhibitor of EGFR, with the inhibition rate of 14% at 1 μM. EGFR-IN-147 has the potential for the research of cancer.

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CAS No.: 91769-08-3
Formule: C₁₃H₁₃N₅O
Masse moléculaire:255.28

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

EGFR-IN-147 Chemical Structure

CAS No.: 91769-08-3

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Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Activité biologique

Description

EGFR-IN-147 (compound ID-5841161) is a potent inhibitor of EGFR, with the inhibition rate of 14% at 1 μM. EGFR-IN-147 has the potential for the research of cancer^[1].

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Chemical Information

CAS No. 91769-08-3
Masse moléculaire 255.28
Formule C₁₃H₁₃N₅O
SMILES

COC(C=C1)=CC=C1NC2=CC(C)=NC3=NC=NN32
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Priya Mahajan, et al. Discovery of novel small molecule EGFR inhibitory leads by structure and ligand-based virtual screening. Med Chem Res 26, 74–92 (2017).

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
Pureté et documentation
Références

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EGFR-IN-147

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