1383561-29-2
Chemical Structure
Cabazitaxel-d6
Synonym(s): XRP6258-d6;RPR-116258A-d6;taxoid XRP6258-d6
- CAS. Nr.: 1383561-29-2
- Formula:C45H51D6NO14
- Molecular Weight:841.97
IUPAC Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-bis(methoxy-d3)-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
InChIKey: BMQGVNUXMIRLCK-YHVGWTKXSA-N
SMILES: CC(O[C@]([C@@]1([H])C[C@@H]2OC([2H])([2H])[2H])(CO1)[C@@]([C@@]2(C([C@@H]3OC([2H])([2H])[2H])=O)C)([H])[C@@H]([C@@](C(C)(C3=C4C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O
Biological Activity: Cabazitaxel-d6 is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Cabazitaxel-d6 | 97.90% | Cabazitaxel-d6 is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. | ||||||||||||||||||||
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Cabazitaxel (Standard) | ≥98% | Cabazitaxel (Standard) is the analytical standard of Cabazitaxel. This product is intended for research and analytical applications. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. | ||||||||||||||||||||
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Cabazitaxel-d9 | 99.06% | Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. | ||||||||||||||||||||
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Cabazitaxel | 99.98% | Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Tai X, et al. Cabazitaxel and indocyanine green co-delivery tumor-targeting nanoparticle for improved antitumor efficacy and minimized drug toxicity. J Drug Target. 2016 Sep 9:1-29. [Content Brief]
