Docetaxel (Standard)
Based on 1 Customer Validation
Docetaxel (Standard) (RP-56976 (Standard)) is the analytical standard of Docetaxel (HY-B0011). This product is intended for research and analytical applications. Docetaxel (RP-56976) is an orally active tubulin stabilizer with antitumor activity. Docetaxel is a P-glycoprotein substrate and is metabolized by CYP3A to inactive products. Docetaxel binds tubulin, promotes tubulin polymerization, and inhibits microtubule depolymerization. Docetaxel induces aberrant mitosis followed by necrotic-like cell death at low concentrations, and induces G2/M mitotic arrest and drives apoptosis at high concentrations. Docetaxel induces renal injury/renal alterations, sex-dependent granule toxicity/uptake, low cardiac delivery, and decreased hepatic SOD/increased catalase/hepatotoxicity. Docetaxel can be used in cancer-related research.
For research use only. We do not sell to patients.
- Purity : 99.92%
- CAS No.: 114977-28-5
- Formula: C43H53NO14
- Molecular Weight:807.88
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-B0015
PaclitaxelAntitumor Agent -
HY-B0011
DocetaxelTubulin Stabilizer -
HY-12053A
Vinorelbine ditartrateAnti-mitotic Agent -
HY-13442
EribulinMicrotubule Inhibitor -
HY-B0015R
Paclitaxel (Standard)Antitumor Agent -
HY-13520
NocodazoleMicrotubule Inhibitor -
HY-16569
ColchicineTubulin Inhibitor -
HY-16565
10-Deacetylbaccatin IIIIntermediate -
HY-10222
IxabepiloneMicrotubule Inhibitor -
HY-N0488
Vincristine sulfateAntineoplastic Agent -
HY-17029
Epothilone BMicrotubule Stabilizer -
HY-16565R
10-Deacetylbaccatin III (Standard)Intermediate
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 114977-28-5
-
Appearance Solid
-
Molecular Weight 807.88
-
Formula C43H53NO14
-
Color White to off-white
-
SMILES
O=C(OC(C)(C)C)N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@@H]2C(C)=C([C@@H](O)C([C@@]3(C)[C@]([C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]3O)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2)=O)O
-
Synonyms
RP-56976 (Standard)
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Docetaxel (Standard) Related Classifications
HY-B0011R Related Classifications
Powered by Bioz