2. Antibody-drug Conjugate/ADC Related
  3. ADC Cytotoxin
  4. Docetaxal

Docetaxal  (Synonyms: 10-Acetyl docetaxel; PNU-101383)

Cat. No.: HY-B0018 Purity: 98.69%
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Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity.

For research use only. We do not sell to patients.

Docetaxal Chemical Structure

Docetaxal Chemical Structure

CAS No. : 125354-16-7

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5 mg USD 50 In-stock
10 mg USD 75 In-stock
25 mg USD 140 In-stock
50 mg USD 220 In-stock
100 mg USD 350 In-stock
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Based on 2 publication(s) in Google Scholar

Docetaxal Related Antibodies

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Description

Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity[1][2].

In Vitro

Docetaxal is an anticancer compound extracted from patent CN107793382A[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Docetaxal Related Antibodies
Molecular Weight

849.92

Formula

C45H55NO15
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(O[C@@]1([C@](C2)([H])OC1)[C@@]([C@](C([C@@H]3OC(C)=O)=O)([C@H]2O)C)([H])[C@@H]([C@@](C(C)(C3=C4C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (117.66 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1766 mL 5.8829 mL 11.7658 mL
5 mM 0.2353 mL 1.1766 mL 2.3532 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1766 mL 5.8829 mL 11.7658 mL 29.4145 mL
5 mM 0.2353 mL 1.1766 mL 2.3532 mL 5.8829 mL
10 mM 0.1177 mL 0.5883 mL 1.1766 mL 2.9415 mL
15 mM 0.0784 mL 0.3922 mL 0.7844 mL 1.9610 mL
20 mM 0.0588 mL 0.2941 mL 0.5883 mL 1.4707 mL
25 mM 0.0471 mL 0.2353 mL 0.4706 mL 1.1766 mL
30 mM 0.0392 mL 0.1961 mL 0.3922 mL 0.9805 mL
40 mM 0.0294 mL 0.1471 mL 0.2941 mL 0.7354 mL
50 mM 0.0235 mL 0.1177 mL 0.2353 mL 0.5883 mL
60 mM 0.0196 mL 0.0980 mL 0.1961 mL 0.4902 mL
80 mM 0.0147 mL 0.0735 mL 0.1471 mL 0.3677 mL
100 mM 0.0118 mL 0.0588 mL 0.1177 mL 0.2941 mL
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Docetaxal Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Docetaxal125354-16-710-Acetyl docetaxel PNU-101383PNU101383PNU 101383PNU-101383ADC CytotoxinADC PayloadDocetaxelanalogmicrotubuledisassemblyantimitoticInhibitorinhibitorinhibit

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