1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. Docetaxal

Docetaxal (Synonyms: 10-Acetyl docetaxel; PNU-101383)

Cat. No.: HY-B0018
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Docetaxal (10-Acetyl docetaxel; PNU-101383), an analog of Docetaxel (HY-B0011), is a microtubule disassembly inhibitor, with antimitotic activity. Docetaxal has cytotoxicity for murine leukemic cells.

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Docetaxal Chemical Structure

Docetaxal Chemical Structure

CAS No. : 125354-16-7

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Description

Docetaxal (10-Acetyl docetaxel; PNU-101383), an analog of Docetaxel (HY-B0011), is a microtubule disassembly inhibitor, with antimitotic activity. Docetaxal has cytotoxicity for murine leukemic cells[1].

In Vitro

Docetaxal has cytotoxicity for murine P388 leukemic cells, with an IC50 of 8.24 μM [1].

Molecular Weight

849.92

Formula

C₄₅H₅₅NO₁₅

CAS No.

125354-16-7

SMILES

CC(O[[email protected]@]1([[email protected]](C2)([H])OC1)[[email protected]@]([[email protected]](C([[email protected]@H]3OC(C)=O)=O)([[email protected]]2O)C)([H])[[email protected]@H]([[email protected]@](C(C)(C3=C4C)C)(C[[email protected]@H]4OC([[email protected]](O)[[email protected]](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O

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Keywords:

Docetaxal10-Acetyl docetaxelPNU-101383PNU101383PNU 101383Microtubule/TubulinDocetaxelanalogmicrotubuledisassemblyantimitoticInhibitorinhibitorinhibit

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