1401034-19-2
1401034-19-2
Chemical Structure
AMG 925 (HCl)
- CAS No.: 1401034-19-2
- Formula:C26H30ClN7O2
- Molecular Weight:508.02
IUPAC Name: 2-hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethan-1-one hydrochloride
InChIKey: JJDSFFVYZSLRLY-AELULUIVSA-N
SMILES: OCC(N1CC2=C(N=C(NC3=NC=C4C(N([C@H]5CC[C@H](C)CC5)C6=CN=CC=C64)=N3)C=C2)CC1)=O.Cl
Biological Activity: AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively.
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AMG 925 (HCl) | AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively. | |||||||||||||||||||||
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Keywords
