1402002-76-9
1402002-76-9
Chemical Structure
PF-06442609
- CAS No.: 1402002-76-9
- Formula:C24H24F4N4O3
- Molecular Weight:492.47
IUPAC Name: 2-((S)-1-(4-fluoro-2-((R)-1,1,1-trifluoropropan-2-yl)phenoxy)propan-2-yl)-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione
InChIKey: XZFBQMFLEPCQCW-JKSUJKDBSA-N
SMILES: O=C1C(N2CCN1[C@@H](C)COC3=CC=C(F)C=C3[C@@H](C)C(F)(F)F)=CC=C(N4C=C(C)N=C4)C2=O
Biological Activity: PF-06442609 is an orally active γ secretase modulator, with an IC50 of 6 nM for Aβ42. PF-06442609 possesses brain good penetration[1].
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PF-06442609 | PF-06442609 is an orally active γ secretase modulator, with an IC50 of 6 nM for Aβ42. PF-06442609 possesses brain good penetration. | |||||||||||||||||||||
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References
Keywords
