1415823-73-2
1415823-73-2
Chemical Structure
Evobrutinib
Synonym(s): M2951; MSC2364447C
- CAS No.: 1415823-73-2
- Formula:C25H27N5O2
- Molecular Weight:429.51
IUPAC Name: 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)prop-2-en-1-one
InChIKey: QUIWHXQETADMGN-UHFFFAOYSA-N
SMILES: C=CC(N1CCC(CNC2=NC=NC(N)=C2C3=CC=C(OC4=CC=CC=C4)C=C3)CC1)=O
Biological Activity: Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases[1].
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Evobrutinib | 99.60% | Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases. | ||||||||||||||||||||
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Evobrutinib (Standard) | ≥98% | Evobrutinib (Standard) is the analytical standard of Evobrutinib (HY-101215). This product is intended for research and analytical applications. Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-139481Flixebrutinib -
Similarity Score 0.54
HY-108318RRK-24466 (Standard) -
Similarity Score 0.54
HY-401475Protein kinase inhibitor 9 -
Similarity Score 0.53
HY-78727Ibrutinib deacryloylpiperidine -
Similarity Score 0.53
HY-179690Antiparasitic agent-30 -
Similarity Score 0.52
HY-13812QNZ -
Similarity Score 0.52
HY-152019EGFR/C797S-IN-1 -
Similarity Score 0.51
HY-118105RK-20448 -
Similarity Score 0.51
HY-15764GA 419259 (GMP) -
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