1453868-32-0
1453868-32-0
Chemical Structure
ENMD-2076 Tartrate
- CAS No.: 1453868-32-0
- Formula:C25H31N7O6
- Molecular Weight:525.56
IUPAC Name: (E)-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine (2R,3R)-2,3-dihydroxysuccinate
InChIKey: KGWWHPZQLVVAPT-STTJLUEPSA-N
SMILES: O=C([C@@H]([C@H](C(O)=O)O)O)O.CC1=CC(NC2=NC(/C=C/C3=CC=CC=C3)=NC(N4CCN(CC4)C)=C2)=NN1
Biological Activity: ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ENMD-2076 Tartrate | 99.66% | ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively. | ||||||||||||||||||||
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ENMD-2076 Tartrate (Standard) | ≥98% | ENMD-2076 Tartrate (Standard) is the analytical standard of ENMD-2076 (Tartrate) (HY-10987). This product is intended for research and analytical applications. ENMD-2076 Tartrate is a multi-targeted Kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KdR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-10987AENMD-2076 -
Similarity Score 0.62
HY-175866Aurora kinase-IN-8 -
Similarity Score 0.60
HY-123159AKI603 -
Similarity Score 0.60
HY-123697VE-465 -
Similarity Score 0.59
HY-10161Tozasertib -
Similarity Score 0.54
HY-181082Aurora kinase-IN-10 -
Similarity Score 0.53
HY-144131RET-IN-11 -
Similarity Score 0.52
HY-1624696K465 -
Similarity Score 0.51
HY-15749XL228 -
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