1454682-72-4
Chemical Structure
LY3009120
Synonym(s): DP-4978
- CAS No.: 1454682-72-4
- Formula:C23H29FN6O
- Molecular Weight:424.51
IUPAC Name: 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea
InChIKey: HHCBMISMPSAZBF-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C2=CC3=CN=C(NC)N=C3N=C2C)=C(C)C=C1F)NCCC(C)(C)C
Biological Activity: LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT with IC50s of 5.8, 9.1 and 15 nM, respectively.
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LY3009120 | 98.66% | LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT with IC50s of 5.8, 9.1 and 15 nM, respectively. | ||||||||||||||||||||
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Keywords