PD-166866 (Standard)
PD-166866 (Standard) is the analytical standard of PD-166866 (HY-101296). This product is intended for research and analytical applications. PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC50 of 52.4 nM.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 192705-79-6
- Formula: C20H24N6O3
- Molecular Weight:396.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 192705-79-6
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Molecular Weight 396.44
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Formula C20H24N6O3
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SMILES
O=C(NC(C)(C)C)NC1=NC2=NC(N)=NC=C2C=C1C3=CC(OC)=CC(OC)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Panek RL, et al. In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase. J Pharmacol Exp Ther. 1998 Jul;286(1):569-77. [Content Brief]
[2]. Thompson AM, Connolly CJ, Hamby JM, et al. 3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase. J Med Chem. 2000;43(22):4200-4211. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)