14769-73-4
14769-73-4
Chemical Structure
Levamisole
Synonym(s): (-)-Tetramisole
- CAS No.: 14769-73-4
- Formula:C11H12N2S
- Molecular Weight:204.30
IUPAC Name: (S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
InChIKey: HLFSDGLLUJUHTE-SNVBAGLBSA-N
SMILES: C12=N[C@@H](C3=CC=CC=C3)CN1CCS2
Biological Activity: Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active[1][2].
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Levamisole | 99.96% | Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active. | ||||||||||||||||||||
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Levamisole (Standard) | ≥98% | Levamisole (Standard) is the analytical standard of Levamisole. This product is intended for research and analytical applications. Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active. | ||||||||||||||||||||
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References
- [1]. Lewis JA, et al. Levamisole: A Positive Allosteric Modulator for the α3β4 Nicotinic Acetylcholine Receptors Prevents Weight Gain in the CD-1 Mice on a High Fat Diet. Curr Pharm Des. 2017;23(12):1869-1872. [Content Brief]
- [2]. Mehta KP, et al. Immunoregulatory treatment for minimal change nephrotic syndrome. Arch Dis Child. 1986;61(2):153-158. [Content Brief]
