148-01-6
Chemical Structure
Dinitolmide
Synonym(s): Zoalene
- CAS No.: 148-01-6
- Formula:C8H7N3O5
- Molecular Weight:225.16
IUPAC Name: 2-methyl-3,5-dinitrobenzamide
InChIKey: ZEFNOZRLAWVAQF-UHFFFAOYSA-N
SMILES: O=C(N)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1C
Biological Activity: Dinitolmide (Zoalene) is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella[1][2].
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Dinitolmide | 99.66% | Dinitolmide (Zoalene) is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella. | ||||||||||||||||||||
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Dinitolmide (Standard) | ≥98% | Dinitolmide (Zoalene) (Standard) is the analytical standard of Dinitolmide (HY-B1004). This product is intended for research and analytical applications. Dinitolmide is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella. | ||||||||||||||||||||
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- [1]. Qu D, et al. Effect of dinitolmide intercalated into Montmorillonite on E. tenella infection in chickens. Parasitol Res. 2014 Mar;113(3):1233-8. [Content Brief]
- [2]. Cao X, et al. In vitro anti-Toxoplasma gondii effects of a coccidiostat dinitolmide. Vet Parasitol. 2023 Apr;316:109903. [Content Brief]
Keywords
