15136-34-2
15136-34-2
Chemical Structure
Cyclo(L-leucyl-L-tryptophyl)
Synonym(s): Cyclo(Leu-Trp)
- CAS No.: 15136-34-2
- Formula:C17H21N3O2
- Molecular Weight:299.37
InChIKey: BZUNCDPEEKFTCX-GJZGRUSLSA-N
SMILES: O=C(N[C@H](C(N1)=O)CC(C)C)[C@@H]1CC2=CNC3=CC=CC=C23
Biological Activity: Cyclo(L-leucyl-L-tryptophyl) (Cyclo(-Leu-Trp)) is a cyclic dipeptide that inhibits a various of bacteria and fungi. Cyclo(L-leucyl-L-tryptophyl) is a melatonin receptor agonist and is also used as a bitter ligand[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cyclo(L-leucyl-L-tryptophyl) | 99.90% | Cyclo(L-leucyl-L-tryptophyl) (Cyclo(-Leu-Trp)) is a cyclic dipeptide that inhibits a various of bacteria and fungi. Cyclo(L-leucyl-L-tryptophyl) is a melatonin receptor agonist and is also used as a bitter ligand. | ||||||||||||||||||||
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References
- [1]. Kumar SN, et al. Purification, structural elucidation and bioactivity of tryptophan containing diketopiperazines, from Comamonas testosteroni associated with a rhabditid entomopathogenic nematode against major human-pathogenic bacteria. Peptides. 2014 Mar;53:48-58. [Content Brief]
- [2]. Zubare-Samuelov M, et al. Some sweet and bitter tastants stimulate inhibitory pathway of adenylyl cyclase via melatonin and alpha 2-adrenergic receptors in Xenopus laevis melanophores. Am J Physiol Cell Physiol. 2003 Nov;285(5):C1255-62. [Content Brief]
- [3]. Shiba T, et al. Some aspects of the relationship between the structure of a bitter diketopiperazine and its receptor. Biopolymers. 1981 Sep;20(9):1985-7. [Content Brief]
