153-87-7
153-87-7
Chemical Structure
Oxypertine
Synonym(s): WIN-18501-2
- CAS No.: 153-87-7
- Formula:C23H29N3O2
- Molecular Weight:379.50
IUPAC Name: 5,6-dimethoxy-2-methyl-3-(2-(4-phenylpiperazin-1-yl)ethyl)-1H-indole
InChIKey: XCWPUUGSGHNIDZ-UHFFFAOYSA-N
SMILES: CC(NC1=C2C=C(OC)C(OC)=C1)=C2CCN3CCN(CC3)C4=CC=CC=C4
Biological Activity: Oxypertine (WIN-18501-2) is a neuroprotective agent. Oxypertine shows high affinity for the 5-HT2 and dopamine D2 receptors with Kis of 8.6 nM and 30 nM, respectively. Oxypertine can be used in the research of neurological conditions, such as anxiety and schizophrenia[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Oxypertine | 99.84% | Oxypertine (WIN-18501-2) is a neuroprotective agent. Oxypertine shows high affinity for the 5-HT2 and dopamine D2 receptors with Kis of 8.6 nM and 30 nM, respectively. Oxypertine can be used in the research of neurological conditions, such as anxiety and schizophrenia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Oxypertine (Standard) | ≥98% | Oxypertine (Standard) is the analytical standard of Oxypertine. This product is intended for research and analytical applications. Oxypertine is a neuroprotective agent. Oxypertine can be used in the research of neurological conditions, such as anxiety and schizophrenia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. H Miranda, et al. Effects of oxypertine on the isolated vas deferens of the rat. Br J Pharmacol. 1978 Apr;62(4):515-8. [Content Brief]
- [2]. T Moroji, et al. Neurochemical and behavioral studies on the mode of action of oxypertine. Arzneimittelforschung. 1986 May;36(5):804-8. [Content Brief]
- [3]. M Hong, et al. Comparison of the acute actions of amine-depleting drugs and dopamine receptor antagonists on dopamine function in the brain in rats. [Content Brief]
- [4]. Megens AA, et al. Risperidone and related 5HT2/D2 antagonists: a new type of antipsychotic agent? Prog Med Chem. 1996;33:185-232. [Content Brief]
Keywords
