154-93-8
Chemical Structure
Carmustine
Synonym(s): BCNU
- CAS 番号: 154-93-8
- Formula:C5H9Cl2N3O2
- Molecular Weight:214.05
IUPAC Name: 1,3-bis(2-chloroethyl)-1-nitrosourea
InChIKey: DLGOEMSEDOSKAD-UHFFFAOYSA-N
SMILES: O=C(NCCCl)N(CCCl)N=O
Biological Activity: Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Carmustine | 99.91% | Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA. | ||||||||||||||||||||
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Carmustine (Standard) | ≥98% | Carmustine (Standard) is the analytical standard of Carmustine. This product is intended for research and analytical applications. Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA. | ||||||||||||||||||||
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Carmustine-d8 | 98.34% | Carmustine-d8 is the deuterium labeled Carmustine. Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA. | ||||||||||||||||||||
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Sarcosinamide chloroethylnitrosourea | Sarcosinamide chloroethylnitrosourea is an orally active alkylating agent. Sarcosinamide chloroethylnitrosourea can induce apoptosis by promoting DNA alkylation. Sarcosinamide chloroethylnitrosourea can be used in cancer-related research. | |||||||||||||||||||||
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Perrimustine | Perrimustine is a cysteamine (CysA) derivative with potent antitumor activity. Perrimustine exhibits significant effect on B16 melanoma and metastasized melanoma cells by causing DNA damage. Perrimustine exhibits antitumor effects in mice bearing various cancers, including lung carcinoma, leukemia, lymphoma, melanoma, colon carcinoma, and glioma. Perrimustine can be used for cancer research, such as melanoma and leukemia. | |||||||||||||||||||||
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Cystemustine | Cystemustine is a DNA inhibitor (a chloroethyl nitrosourea, CENU). Cystemustine can cause DNA cross-linking, thereby inhibiting the proliferation of tumor cells. Cystemustine can also exert cytotoxic effects by interfering with the cell cycle, inducing cell re-differentiation, and altering phospholipid metabolism. Cystemustine exhibits high anti-tumor activity and a relatively short plasma half-life in mice. Cystemustine can be used for the study of various malignant tumors, including melanoma, glioma, renal cancer, head and neck cancer, and colorectal cancer, etc. | |||||||||||||||||||||
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Elmustine | Elmustine (HECNU) is a DNA inhibitor. Elmustine can be used for the research of cancer. | |||||||||||||||||||||
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Lomustine (Standard) | 99.94% | Lomustine (Standard) is the analytical standard of Lomustine. This product is intended for research and analytical applications. Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity. | ||||||||||||||||||||
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N-(4-Azidobutyl)-2-chloroacetamide | N-(4-Azidobutyl)-2-chloroacetamide is a PROTAC linker that can be used for the synthesis of PROTACs, such as PROTAC Sirt2 Degrader-1 (HY-103636). | |||||||||||||||||||||
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1,3-Bis(2-chloroethyl)urea (Standard) | ≥98% | 1,3-Bis(2-chloroethyl)urea (Standard) is the analytical standard of 1,3-Bis(2-chloroethyl)urea. This product is intended for research and analytical applications. | ||||||||||||||||||||
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N,N'-(Pentane-1,5-diyl)bis(2-chloroacetamide) | N,N'-(Pentane-1,5-diyl)bis(2-chloroacetamide) is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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N-Nitroso-tris-chloroethylurea | N-Nitroso-tris-chloroethylurea is a DNA-alkylating chemical carcinogen and a trichloronitrosamine derivative. N‑Nitroso‑tris‑chloroethylurea induces a series of pathological changes such as bronchial hyperplasia, metaplasia, and atypical hyperplasia, ultimately driving the formation of lung squamous cell carcinoma. N-nitroso-tris-chloroethylurea can be used to establish chemically induced lung squamous cell carcinoma models. N-Nitroso-tris-chloroethylurea can be used in research related to lung squamous cell carcinoma. | |||||||||||||||||||||
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Bis(2-chloroethyl)amine hydrochloride | 98.0% | Bis(2-chloroethyl)amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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