1541170-75-5
1541170-75-5
Chemical Structure
Sonlicromanol
Synonym(s): KH176
- CAS No.: 1541170-75-5
- Formula:C19H28N2O3
- Molecular Weight:332.44
IUPAC Name: (S)-6-hydroxy-2,5,7,8-tetramethyl-N-((R)-piperidin-3-yl)chromane-2-carboxamide
InChIKey: LZYWLEPSQNXESC-KUHUBIRLSA-N
SMILES: CC1=C(C(C)=C2CC[C@@](C(N[C@@H]3CCCNC3)=O)(OC2=C1C)C)O
Biological Activity: Sonlicromanol (KH176) is an orally active reactive oxygen species (ROS) modulator for the study in mitochondrial disease[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sonlicromanol | 98.65% | Sonlicromanol (KH176) is an orally active reactive oxygen species (ROS) modulator for the study in mitochondrial disease. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-120332Sonlicromanol hydrochloride -
Similarity Score 0.78
HY-123461Sul-121 hydrochloride -
Similarity Score 0.70
HY-101445A(R)-Trolox -
Similarity Score 0.70
HY-101445BR(S)-Trolox (Standard) -
Similarity Score 0.70
HY-101445RTrolox (Standard) -
Similarity Score 0.65
HY-113269Ralpha-CEHC (Standard) -
Similarity Score 0.64
HY-111024R2,2,5,7,8-Pentamethyl-6-Chromanol (Standard) -
Similarity Score 0.63
HY-116757(±)-α-CMBHC -
Similarity Score 0.56
HY-113095γ-CEHC -
Explore the MedChemAI to find more analogs
References
- [1]. X Jiang, et al. Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE 2 biosynthesis by sonlicromanol's metabolite KH176m. Sci Rep. 2021 Jan 13;11(1):880. [Content Brief]
- [2]. Zikai Feng, et al. Comparative In Vitro Toxicology of Novel Cytoprotective Short-Chain Naphthoquinones. Pharmaceuticals (Basel). 2020 Aug 7;13(8):184. [Content Brief]
