1607428-33-0
1607428-33-0
Chemical Structure
OX2-2303
- CAS No.: 1607428-33-0
- Formula:C23H21FN4O2S
- Molecular Weight:436.50
InChIKey: BRNNGDLYXKPTJY-RDTXWAMCSA-N
SMILES: FC1=CC(C(N2C[C@H](OC3=NC=CC(C#N)=C3C)CC[C@H]2C)=O)=C(C4=NC=CS4)C=C1
Biological Activity: OX2-2303 is a potent, selective orexin-2 receptor (OX2R) antagonist. OX2-2303 exhibits excellent binding affinity towards OX2R (Ki = 0.1 nM), and shows >890-fold selectivity over OX1R. OX2-2303 can be used as a positron emission tomography (PET) radioligand for central nervous system (CNS) research[1].
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OX2-2303 | OX2-2303 is a potent, selective orexin-2 receptor (OX2R) antagonist. OX2-2303 exhibits excellent binding affinity towards OX2R (Ki = 0.1 nM), and shows >890-fold selectivity over OX1R. OX2-2303 can be used as a positron emission tomography (PET) radioligand for central nervous system (CNS) research. | |||||||||||||||||||||
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