1615-02-7
Chemical Structure
4-Chlorocinnamic acid
- CAS No.: 1615-02-7
- Formula:C9H7ClO2
- Molecular Weight:182.61
IUPAC Name: (E)-3-(4-chlorophenyl)acrylic acid
InChIKey: GXLIFJYFGMHYDY-ZZXKWVIFSA-N
SMILES: O=C(O)/C=C/C1=CC=C(Cl)C=C1
Biological Activity: 4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A). 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0.477 mM and 0.229 mM, respectively. 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides. 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Chlorocinnamic acid | 99.93% | 4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A). 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0.477 mM and 0.229 mM, respectively. 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides. 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol. | ||||||||||||||||||||
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- [1]. Cui Y, et al. Inhibition kinetics and molecular simulation of p-substituted cinnamic acid derivatives on tyrosinase. Int J Biol Macromol. 2017 Feb;95:1289-1297. [Content Brief]
- [2]. Silva RHN, et al. Antimicrobial Activity of 4-Chlorocinnamic Acid Derivatives. Biomed Res Int. 2019 Apr 23;2019:3941242. [Content Brief]
- [3]. Kátia Aparecida de Siqueira, et al. Isolation of 4-chlorocinnamic acid from Streptomyces griseocarneus R132, and its inhibition activity against sweet pepper postharvest anthracnose. Biocontrol Science and Technology. Volume 32, 2022-Issue 6
- [4]. Cuan Y, et al. Anticonvulsant Activity of Halogen-Substituted Cinnamic Acid Derivatives and Their Effects on Glycosylation of PTZ-Induced Chronic Epilepsy in Mice. Molecules. 2017 Dec 29;23(1):76. [Content Brief]
Keywords
