171335-80-1
171335-80-1
Chemical Structure
Exatecan
Synonym(s): DX-8951
- CAS No.: 171335-80-1
- Formula:C24H22FN3O4
- Molecular Weight:435.45
IUPAC Name: (1S,9S)-1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H,13H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione
InChIKey: ZVYVPGLRVWUPMP-FYSMJZIKSA-N
SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O
Biological Activity: Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Exatecan | 99.96% | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. | ||||||||||||||||||||
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Exatecan (Standard) | 99.89% | Exatecan (Standard) is the analytical standard of Exatecan. This product is intended for research and analytical applications. Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. | ||||||||||||||||||||
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Exatecan-d3 mesylate | Exatecan-d3 (DX8951f-d3) mesylate is deuterium-labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 0.975 μg/mL. | |||||||||||||||||||||
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