17238-05-0
Chemical Structure
Dihydrodaidzein
Synonym(s): (±)-Dihydrodaidzein
- CAS No.: 17238-05-0
- Formula:C15H12O4
- Molecular Weight:256.26
IUPAC Name: 7-hydroxy-3-(4-hydroxyphenyl)chroman-4-one
InChIKey: JHYXBPPMXZIHKG-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C(O)C=C2)COC3=CC(O)=CC=C13
Biological Activity: Dihydrodaidzein is a dietary phytoestrogen. Dihydrodaidzein possesses functions including antioxidation, inhibition of DNA oxidative damage, regulation of lipid metabolism and maintenance of intestinal flora stability. Dihydrodaidzein induces apoptosis, regulates immune responses, modulates tumor-related factors, activates the Bmp-2 signaling pathway, inhibits NF-κB and MAPK, and exhibits anti-inflammatory activity. Dihydrodaidzein can be used in research related to cancer, cardiovascular diseases, osteoporosis and inflammatory diseases[1][2][3][4][5].
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Dihydrodaidzein | 99.38% | Dihydrodaidzein is a dietary phytoestrogen. Dihydrodaidzein possesses functions including antioxidation, inhibition of DNA oxidative damage, regulation of lipid metabolism and maintenance of intestinal flora stability. Dihydrodaidzein induces apoptosis, regulates immune responses, modulates tumor-related factors, activates the Bmp-2 signaling pathway, inhibits NF-κB and MAPK, and exhibits anti-inflammatory activity. Dihydrodaidzein can be used in research related to cancer, cardiovascular diseases, osteoporosis and inflammatory diseases. | ||||||||||||||||||||
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Dihydrodaidzein (Standard) | ≥98% | Dihydrodaidzein (Standard) ((±)-Dihydrodaidzein (Standard)) is the analytical standard of Dihydrodaidzein (HY-N1461). This product is intended for research and analytical applications. Dihydrodaidzein is a dietary phytoestrogen. Dihydrodaidzein possesses functions including antioxidation, inhibition of DNA oxidative damage, regulation of lipid metabolism and maintenance of intestinal flora stability. Dihydrodaidzein induces apoptosis, regulates immune responses, modulates tumor-related factors, activates the Bmp-2 signaling pathway, inhibits NF-κB and MAPK, and exhibits anti-inflammatory activity. Dihydrodaidzein can be used in research related to cancer, cardiovascular diseases, osteoporosis and inflammatory diseases. | ||||||||||||||||||||
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References
- [1]. Schröder C, et al. Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens. Applied and environmental microbiology. 2013 Jun;79(11):3494-502. [Content Brief]
- [2]. Franke AA, et al. Liquid chromatographic-photodiode array mass spectrometric analysis of dietary phytoestrogens from human urine and blood. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Sep 25;777(1-2):45-59. [Content Brief]
- [3]. Ubaid M, et al. Daidzein from Dietary Supplement to a Drug Candidate: An Evaluation of Potential. ACS omega. 2023 Sep 12;8(36):32271-32293. [Content Brief]
- [4]. Shimada Y, et al. Cloning and expression of a novel NADP(H)-dependent daidzein reductase, an enzyme involved in the metabolism of daidzein, from equol-producing Lactococcus strain 20-92. Applied and environmental microbiology. 2010 Sep;76(17):5892-901. [Content Brief]
- [5]. Zou P, et al. Advances on resource, biosynthesis pathway, bioavailability, and bioactivity of dihydrodaidzein. Phytochem Rev. 2025;24:3915-3940.
